In central nervous system (CNS) clinical research, placebo response remains one of the greatest barriers to demonstrating efficacy — often leading to inconclusive results, failed studies, and costly delays.
This white paper examines the why behind placebo response and provides expert strategies to manage it effectively, from rater training and site oversight to trial design and technology integration. Download it now to:
- Unpack the drivers of high placebo response in CNS trials
- Explore proven and emerging management strategies
- Learn best practices for layered placebo management, emphasizing trial simplicity, strong site oversight, and proactive data monitoring
- See how partnering with a specialty CNS CRO enhances signal detection, reduces variability, and improves trial success rates
It’s time to design smarter studies that improve confidence in your data — and your chances of approval.